In this study, researchers showed a synergistic effect of the auxin herbicide 2,4-D amine with the PSII-inhibiting herbicide metribuzin to control the global grass weed wild oat (Avena sterilis) population and investigated the underlying mechanisms.
Most Australian crop farm populations of the grass weed Lolium rigidum are multiple herbicide-resistant. Most resistant populations exhibit target site mutations (e.g. ACCase, ALS), as well as metabolic resistance due to cytochrome P450, catalysed by enhanced rates of herbicide metabolism.